MM 11253( MM-11253 )

Catalog No. M27662 CAS No. 345952-44-5

MM 11253 is a RARγ antagonist with IC50 of 44nM.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Biological Information

Product Name

MM 11253
Note

Research use only, not for human use.
Brief Description

MM 11253 is a RARγ antagonist with IC50 of 44nM.
Description

MM 11253 is a RARγ antagonist with IC50 of 44nM.(In Vitro):MM11253 blocks the ability of MM11254 and MM11389 to inhibit squamous cell carcinoma cell growth .
In Vitro

MM11253 blocks the ability of MM11254 and MM11389 to inhibit squamous cell carcinoma cell growth.
In Vivo

——
Synonyms

MM-11253
Pathway

Metabolic Enzyme/Protease
Target

Retinoid Receptor
Recptor

AMPK α2β2γ1|AMPK α1β1γ1|AMPK α2β1γ1|AMPK α1β2γ1
Research Area

——
Indication

——

Chemical Information

CAS Number

345952-44-5
Formula Weight

462.67
Molecular Formula

C28H30O2S2
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 125 mg/mL (270.17 mM)
SMILES

CC1(C)CCC(C)(C)c2cc(ccc12)C1(SCCS1)c1ccc2cc(ccc2c1)C(O)=O
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Zhang LN, et al. Novel small-molecule AMP-activated protein kinase allosteric activator with beneficial effects in db/db mice. PLoS One. 2013 Aug 20;8(8):e72092.

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